บทคัดย่องานวิจัย

Genetics and physiology of aflatoxin biosynthesis.

PAYNE, G.A. and BROWN, M.P.

Annual Review of Phytopathology 36: 329 – 362.

1998

บทคัดย่อ

Genetics and physiology of aflatoxin biosynthesis.

A review with 140 references. Genetic studies on aflatoxin biosynthesis in Aspergillus flavus and A. parasiticus, and sterignatocystin biosynthesis in A. nidulans, led to the cloning of 17 genes responsible for 12 enzymatic conversions in the aflatoxin / sterigmatocystin pathways. Less is known about the global factors that regulate aflatoxin biosynthesis, but there is a clear link between development and aflatoxin biosynthesis. There is also a large body of information on physiological factors involved in aflatoxin biosynthesis. This chapter discusses current knowledge on the molecular biology and genetics of the pathway and provides a summary of the physiological factors known to influence aflatoxin formation.