Formation of N – (carboxymethyl) fumonisin B1, following the reaction of fumonisin B1 with reducting sugars.
HOWARD, P.C., CHURCHWELL, M.I., COUCH, C.H., MARQUES, M.M. and DOERGE, D.R.
Journal of Agricultural and Food Chemistry 46: 3546 – 3557.
1998
บทคัดย่อ
Several reports have indicated that FB1 concentrations decreased when heated in aqueous solutions of reducing sugars. This study showed that the incubation of FB1 with D – glucose resulted in the formation of N- (carboxymethyl) FB1, which was characterised by NMR and electrospray MS. N- (carboxymethyl) FB1 arises from Schiffs base formation, Amadori rearragngement to a B- ketoamine and oxidation with molecular oxygen. N- (carboxymethyl) FB1 formation is favoured by alkaline conditions, requires molecular oxygen and is catalysed by several reducing sugars. N- (carboxymethyl) FB1 was detected in raw corn samples that contained FB1 (0.5 – 1.4 mg/kg) at an average of 4% of the FB1 levels.