บทคัดย่องานวิจัย

Prospects for reducing fumonisin contamination of maize through genetic modification.

DUVICK, J.

Environmental Health Perspectives 109: 337 – 342.

2001

บทคัดย่อ

Prospects for reducing fumonisin contamination of maize through genetic modification.

Among the strategies for reducing risk of fumonisin contamination in maize supplied to the market, the development and deployment of Fusarium ear mould resistant maize germplasm is a high priority. Breeding for increased ear mould tolerance and reduced mycotoxin levels is being practiced today but the amount of resistance achievable may be limited due to complicated genetics and/ or linkage to undesirable agronomic traits. Transgenic approaches to ear mould/ mycotoxin resistance are now feasible as well. One example is already on the market, namely transgenic maize expressing Bacillus thuringiensis Bt toxin targeted to the European corn borer. A second approach, transgene mediated control of the ability of Fusarium to infect and colonixe the ear, could potentially be achieved through over-expression of specific antifungal proteins and metabolites, or enhancement of the plant’s own defence systems in kernel tissues. A third approach is transgene strategies aimed at preventing mycotoxin biosynthesis, or detoxifying mycotoxins in plants. In one example of such a strategy, enzymes that degrade fumonisins have been identified in a filamentous saprophytic fungus isolated from maize, and corresponding genes have been cloned and are currently being tested in transgenic maize.