บทคัดย่องานวิจัย

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Requirement of Ca2 for aflatoxin production: inhibitory effect of Ca2 channel blockers on aflatoxin production by Aspergillus parasiticus NRRL 2999

RAO, J.P. and SUBRAMMANYAM, C.

Letters in Applied Microbiology 28: 85-88.

1999

บทคัดย่อ

Requirement of Ca2+ for aflatoxin production: inhibitory effect of Ca2+ channel blockers on aflatoxin production by Aspergillus parasiticus NRRL 2999.

Aflatoxin production by Aspergillus parasiticus was inhibited when Ca2+ channel blockers, verapamil and diltiazem, were included in the culture medium. Inhibition was not accompanied by growth inhibition, nor was the [14C]-glucose uptake by the organism altered. However, both the compounds inhibited  [14C]-acetate incorporation into AFB1 in a dose dependent manner and decreased sporulation of the organism.