บทคัดย่องานวิจัย

Total synthesis of fumitremorgins and verruculogens.

HINO, T. and NAKAGAWA, M.

Heterocycles 46 : 673-704.

1997

บทคัดย่อ

Total synthesis of fumitremorgins and verruculogens.

A review with 81 references.  The syntheses of fumitremorgin B, C, verruculogen TR-2 and related compounds, all of which are pentacyclic tremorgenic mycotoxins, are reviewed.  Major topics include construction of the pentacyclic ring system, stereoselective formation of 1,3-disubstituted beta-carboline and introduction of a double bond and cis glycol to the ring C of the pentacycle.